OPTIC NEURITIS FOLLOWING SARS-COV-2 INFECTION IN A CHILD
To report a rare case of optic neuritis in a child following SARS-CoV-2 infection associated with poor visual outcome.
A 13-YO Caucasian girl was referred for neuro-ophthalmologic examination 2 months after developing blurred vision and pain in the left eye (OS), one month following SARS-CoV-2 infection. BCVA was 20/20 in the right eye OD, and 20/200 OS. Fundus examination showed hyperemia of the optic disc and venous congestion in the OS. She could read 10/10 of the Ishihara color plates OD, and 6/10 plates OS. There was temporal hemianopia on field visaul field OS. The remaining of the neurological examination was unremarkable. OCT showed macular thickness was slightly decreased in both eyes (< 5%). Serum search for AQP4-IgG was unrevealing whereas search for MOG-IgG was not performed. Cerebrospinal fluid analysis disclosed 3 cells/mm3 (60% were neutrophils), and protein content of 24 mg%. Search for CSF specific oligoclonal bands was not performed. Brain MRI showed a small T2-hyperintense lesion in the intraorbital segment of the left optic nerve with no gadolinium enhancement. The patient received IV pulses of methylprednisolone for 5 days but had no visual recovery.
Most cases of optic neuritis follow ing SARS-CoV-2 infection have been reported in adults. However, we need to be aware of this manifestation in children. Our patient was a child who developed optic neuritis one month after COV ID-19. Only two months later she was given IV pulses of steroids with no response.
Optic neuritis; SARS-CoV-2, child
Neuro-oftalmologia
Centro de Investigação de Esclerose Múltipla da Universidade Federal de Minas Gerais - Minas Gerais - Brasil
Luciana Maria Rocha Biscaro, Grazielle Fialho Souza, Hugo Brito, Juliana Santiago, Paulo P Christo, Marco Aurelio Lana-Peixoto
