Título / Title

AGE-STRATIFIED MACULAR RETINAL AND CHOROIDAL ARCHITECTURE STANDARDS: INSIGHTS FROM A STUDY OF HEALTHY BRAZILIAN ADULTS

Introdução / Purpose

Optical Coherence Tomography enables the quantitative and reliable measurement, detection, and monitoring of subtle changes in the thickness and volume of the retina and choroid.While international studies standardize retinal and choroidal thickness values, the absence of specific standardization in Brazil, and its potential variation across ethnicities, motivates this study.The aim is to establish values for retinal thickness and volume, as well as choroidal thickness in healthy Brazilians, correlating them with age, gender and axial length of the eyeball (AXL)

Material e Método / Methods

This is a cross-sectional, non-interventional study in which healthy patients underwent evaluation using SD-OCT. The protocol includes 30 horizontal and 5 vertical scans centered on the foveola. Retinal thickness and volume values are derived from the macular ETDRS grid, while choroidal thickness is manually measured at specific points, forming a topographical map with thickness averages for each subfield of the ETDRS grid.The analysis considers variables such as age, gender and AXL

Resultados / Results

211 participants were evaluated (102 men/109 women). The mean central retinal thickness was 271.15±22.56 μm, and the volume was 0.21±0.02 mm³.Men exhibited greater retinal thickness/volume. Older individuals showed lower retinal thickness/volume, except in the central subfield. There was a positive correlation between AXL and central retinal thickness/volume.Regarding the choroid, the mean central thickness was 301.34±84.02μm. There was no significant difference between genders, but a reduction in thickness was observed with advancing age and greater AXL

Discussão e Conclusões / Conclusion

This study proposes specific normative values for the Brazilian population, considering factors such as age, gender, and AXL. The obtained results will contribute to filling a gap in ophthalmic standards research, providing data that can support variations among different ethnicities, and more precisely guide the assessment and monitoring of macular pathologies in Brazilian patients

Palavras Chave

Retinal thickness; Retinal volume; Choroidal thickness; Healthy population; Standardization; OCT

Area

CLINICAL RETINA

Institutions

Hospital das Clínicas de Ribeirão Preto - USP - Ribeirão Preto - São Paulo - Brasil

Authors

MOISÉS MOURA DE LUCENA, RENATO PERONI, LEONARDO LUIS CASSONI, CAROLINE GIACOMELLI, JOÃO PEDRO ROMERO BRAGA, ANDRE MÁRCIO VIEIRA MESSIAS, JAY CHHABLANI, RODRIGO JORGE